Yuhua Wang Selected Research

Small Interfering RNA (siRNA)

1/2016	PolyMetformin combines carrier and anticancer activities for in vivo siRNA delivery.
9/2015	PU.1 affects proliferation of the human acute myeloid leukemia U937 cell line by directly regulating MEIS1.
4/2014	Nanoparticle-delivered transforming growth factor-β siRNA enhances vaccination against advanced melanoma by modifying tumor microenvironment.
11/2013	Incorporation of histone derived recombinant protein for enhanced disassembly of core-membrane structured liposomal nanoparticles for efficient siRNA delivery.
10/2013	Intravenous delivery of siRNA targeting CD47 effectively inhibits melanoma tumor growth and lung metastasis.
10/2013	Reply to "On the mechanism and benefit of siRNA-mediated targeting of CD47 in cancer".
8/2012	Nanoparticle delivery of pooled siRNA for effective treatment of non-small cell lung cancer.
4/2011	Development of targeted recombinant polymers that can deliver siRNA to the cytoplasm and plasmid DNA to the cell nucleus.

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Yuhua Wang Research Topics

Disease

37	Neoplasms (Cancer) 09/2021 - 09/2009
12	Psoriasis (Pustulosis Palmaris et Plantaris) 11/2020 - 02/2007
12	Melanoma (Melanoma, Malignant) 01/2018 - 10/2013
11	Inflammation (Inflammations) 11/2021 - 01/2013
8	Fatty Liver 02/2020 - 07/2012
7	Psoriatic Arthritis 11/2020 - 08/2013
6	Alcoholic Liver Diseases (Alcoholic Liver Disease) 04/2016 - 12/2011
5	Breast Neoplasms (Breast Cancer) 12/2016 - 07/2009
5	Hypoxia (Hypoxemia) 04/2014 - 12/2011
4	Neoplasm Metastasis (Metastasis) 03/2014 - 08/2012
3	Infections 01/2022 - 08/2017
3	Lung Neoplasms (Lung Cancer) 09/2021 - 11/2015
3	Body Weight (Weight, Body) 01/2021 - 10/2010
3	Obsessive-Compulsive Disorder (Disorder, Obsessive-Compulsive) 01/2020 - 09/2016
3	Endotoxemia 04/2016 - 07/2012
2	Fibrosis (Cirrhosis) 07/2022 - 01/2014
2	Sepsis (Septicemia) 10/2021 - 03/2020
2	Obesity 08/2021 - 06/2015
2	Wounds and Injuries (Trauma) 08/2021 - 11/2018
2	Autoimmune Diseases (Autoimmune Disease) 08/2021 - 03/2015
2	Alveolar Bone Loss 01/2021 - 08/2017
2	Leukemia 01/2021 - 09/2015
2	Septic Shock (Toxic Shock Syndrome) 03/2020 - 02/2020
2	Stroke (Strokes) 01/2019 - 01/2018
2	Necrosis 01/2018 - 06/2014
2	Brain Neoplasms (Brain Tumor) 01/2018 - 01/2012
2	Non-alcoholic Fatty Liver Disease 01/2018 - 06/2015
2	Periodontal Diseases (Periodontal Disease) 01/2017 - 01/2016
2	Dehydration (Water Stress) 01/2016 - 03/2014
2	Muscle Cramp (Cramp) 05/2013 - 07/2012
2	Myocardial Infarction 10/2012 - 01/2012

Drug/Important Bio-Agent (IBA)

12	Proteins (Proteins, Gene)FDA Link 11/2021 - 12/2011
11	Ustekinumab (CNTO 1275)FDA Link 01/2022 - 05/2008
10	LipidsIBA 10/2017 - 07/2003
9	Pharmaceutical PreparationsIBA 01/2020 - 09/2013
9	Monoclonal AntibodiesIBA 01/2018 - 02/2007
8	Small Interfering RNA (siRNA)IBA 01/2016 - 04/2011
7	Messenger RNA (mRNA)IBA 01/2021 - 07/2012
6	AntigensIBA 01/2021 - 11/2013
6	EndotoxinsIBA 03/2020 - 12/2011
6	VaccinesIBA 01/2018 - 04/2014
6	Interleukin-12 (IL 12)IBA 06/2014 - 02/2007
5	LipopolysaccharidesIBA 01/2022 - 02/2020
5	CytokinesIBA 08/2021 - 02/2007
5	Peptides (Polypeptides)IBA 01/2018 - 07/2009
5	InterleukinsIBA 01/2018 - 05/2008
5	Cisplatin (Platino)FDA LinkGeneric 01/2016 - 01/2014
4	AntioxidantsIBA 11/2021 - 08/2021
4	Ethanol (Ethyl Alcohol)IBA 01/2021 - 01/2013
4	Phosphoric Monoester Hydrolases (Phosphatases)IBA 01/2021 - 03/2016
4	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2021 - 09/2013
4	Tyrosine (L-Tyrosine)FDA Link 01/2021 - 03/2016
4	C-Reactive ProteinIBA 11/2020 - 08/2013
3	Therapeutic UsesIBA 09/2021 - 02/2011
3	RNA (Ribonucleic Acid)IBA 01/2021 - 08/2012
3	CollagenIBA 01/2021 - 11/2015
3	guselkumabIBA 11/2020 - 04/2014
3	Triglycerides (Triacylglycerol)IBA 02/2020 - 07/2012
3	DNA (Deoxyribonucleic Acid)IBA 12/2019 - 07/2009
3	NanovaccinesIBA 01/2018 - 11/2015
3	Phosphotransferases (Kinase)IBA 01/2018 - 03/2011
3	Interleukin-23 (Interleukin 23)IBA 01/2018 - 04/2014
3	calcium phosphateIBA 10/2017 - 09/2013
3	Protamines (Protamine Sulfate)FDA Link 01/2017 - 08/2012
3	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2017 - 05/2012
3	peptide SVYDFFVWLIBA 02/2016 - 11/2013
3	Liposomes (Liposome)IBA 01/2016 - 02/2013
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2016 - 08/2012
3	Biological ProductsIBA 06/2014 - 08/2013
2	Polysaccharides (Glycans)IBA 09/2021 - 02/2020
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2021 - 03/2014
2	Complementary DNA (cDNA)IBA 01/2021 - 03/2014
2	6-methyladenineIBA 01/2021 - 01/2021
2	Interleukin-10 (Interleukin 10)IBA 01/2021 - 03/2015
2	Interleukin-6 (Interleukin 6)IBA 01/2021 - 09/2019
2	porphyranIBA 03/2020 - 02/2020
2	CholesterolIBA 02/2020 - 08/2018
2	Indicators and Reagents (Reagents)IBA 01/2020 - 11/2016
2	Doxorubicin (Adriamycin)FDA LinkGeneric 05/2018 - 12/2016
2	Glucose (Dextrose)FDA LinkGeneric 01/2018 - 07/2003
2	CopperIBA 01/2018 - 06/2015
2	MicroRNAs (MicroRNA)IBA 01/2018 - 01/2014
2	mRNA VaccinesIBA 01/2018 - 01/2018
2	FructoseIBA 01/2018 - 06/2015
2	Neoplasm Antigens (Tumor Antigens)IBA 01/2018 - 04/2014
2	MicellesIBA 10/2017 - 02/2016
2	Mannose (D-Mannose)IBA 10/2017 - 04/2014
2	CPG-oligonucleotideIBA 01/2017 - 04/2014
2	ametantrone (HAQ)IBA 12/2016 - 06/2014
2	Corn Oil (Oil, Corn)IBA 04/2016 - 05/2013
2	Unsaturated FatsIBA 04/2016 - 05/2013
2	Oxygen (Dioxygen)IBA 03/2016 - 10/2012
2	Amino Acids FDA Link 01/2016 - 02/2015
2	Fatty Acids (Saturated Fatty Acids)IBA 02/2015 - 04/2014

Therapy/Procedure

23	Therapeutics 01/2022 - 06/2010
5	Immunotherapy 01/2018 - 11/2013
4	Drug Therapy (Chemotherapy) 01/2021 - 02/2013
3	Ligation 10/2021 - 08/2017
2	Precision Medicine 11/2015 - 01/2012
2	Intravenous Injections 11/2012 - 08/2012